Can you just stop taking raloxifene? (2023)

Can you just stop taking raloxifene?

Do not take more or less of it or take it more often than prescribed by your doctor. Continue to take raloxifene even if you feel well. Do not stop taking raloxifene without talking to your doctor.

discontinuation). Patients, who discontinued alendronate therapy experienced an increase in bone turnover. Bone turnover increases were less pronounced in patients taking raloxifene and were absent in those who continued alendronate.

Abstract. Background: Due to the chronic nature of osteoporosis and the risk of invasive breast cancer, raloxifene 60 mg/day (raloxifene) is intended to be used for long-term treatment (treatment >3 years).

Yes. Weight gain is one of the common side effects of Raloxifene. Although weight gain can occur on the administration of this medication, it may be overcome by a shorter average duration of therapy on Raloxifene.

After an average of 81 months, (5 years of medication and 21 months of followup) women in the tamoxifen group had 247 cases of invasive breast cancer in 9,736 women and women in the raloxifene group had 310 cases of invasive breast cancer in 9,754 women.

Conclusion: Raloxifene may have some benefit for cognition, but it is not significant effect on anxiety, depression, sleep, sexual function, vasomotor symptoms and worsens menstrual symptoms.

WARNING: Raloxifene may rarely cause serious blood clots, especially in the legs or lungs. Women who have or had blood clots (including in the legs, lungs, or eyes) should not take raloxifene.

The significant 25% reduction in global index (150 fewer events per 10,000 women taking raloxifene for an average of 3.4 years) is compatible with a favorable risk-benefit safety profile when raloxifene is used for osteoporosis treatment in postmenopausal women.

Serum enzyme elevations are uncommon during raloxifene therapy and are rarely dose limiting. While clinically apparent liver injury with jaundice has been reported with raloxifene therapy, it is very rare. Evaluation should include assessment of hepatic steatosis by ultrasound or other imaging modalities.

Does raloxifene cause eye problems?

Evista may infrequently cause stroke or serious blood clots to form in the legs, lungs, or eyes.

In these trials, patients were evaluated for up to eight years. While available information is supportive of EVISTA use for more than three years, the optimum duration of EVISTA therapy is not known.

Conclusions: These preliminary results suggest that raloxifene does not negatively influence mood in non-depressed, younger postmenopausal women. Larger, long-term studies are required to evaluate a possible mood improvement effect of raloxifene.

Venous Thromboembolism: The most serious adverse reaction related to Evista was VTE (deep venous thrombosis, pulmonary embolism, and retinal vein thrombosis). During an average of study-drug exposure of 2.6 years, VTE occurred in about 1 out of 100 patients treated with Evista.

Raloxifene lowers the blood concentrations of total and low-density lipoprotein (LDL) cholesterol, the bad cholesterols, but it does not increase concentrations of high-density lipoprotein (HDL) cholesterol, the good cholesterol, in your blood.

Raloxifene - Chemotherapy Drugs - Chemocare.

Raloxifene had no significant effect on depression and sleep disorder, but decrease the concentration of lipoprotein. Raloxifene was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and POP in post- menopausal women.

These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Some of the serious side effects of Raloxifene are: Insomnia. Sweating.

Before starting Evista, tell your doctor if you have had blood clots in your legs, lungs, or eyes, a stroke, mini-stroke (transient ischemic attack), or have an irregular heartbeat. 2. Stop taking Evista and call your doctor if you have: leg pain or a feeling of warmth in the lower leg (calf).

Can you drink with raloxifene?

Alcohol is unlikely to interact with raloxifene. However, heavy drinking is a risk factor for osteoporosis and for having falls so it's recommended that you drink alcohol only in moderation.

Contraindications to raloxifene include past medical history of deep venous thrombosis, renal vein thrombosis, pulmonary embolism, malignancy, active smoking, or any thrombophilia (factor V Leiden deficiency, prothrombin gene mutation G20210A, antiphospholipid syndrome, deficiency of antithrombin, protein c and s ...

Raloxifene is used to help prevent and treat thinning of the bones (osteoporosis) only in postmenopausal women. It works like an estrogen to stop the bone loss that can develop in women after menopause, but it does not increase the bone density as much as daily 0.625 mg doses of conjugated estrogens.

Raloxifene therapy also reduced serum LDL-C level and was well tolerated. For these reasons, raloxifene should be considered as an adjunct to exercise and nutritional optimization for long-term osteoporosis prevention in healthy postmenopausal women with risk factors for osteoporosis.

What drugs and food should I avoid while taking Evista (Raloxifene)? If you take calcium supplements, do not take more than your doctor has prescribed. Taking more calcium than recommended will not provide extra protection for your bones, and may cause serious side effects including kidney stones.

It seems that treatment with raloxifene does not influence back pain and disability among postmenopausal women with osteoporosis. Raloxifene may have estrogenic agonist effects on nociceptive processing in the central nervous system.

Raloxifene is used by women to prevent and treat bone loss (osteoporosis) after menopause. It slows down bone loss and helps to keep bones strong, making them less likely to break. Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive breast cancer) after menopause.

The package inserts of selective estrogen receptor modulators, such as raloxifene (Evista) and tamoxifen (Nolvadex), list hot flushes and night sweats as a common side effect.

Raloxifene will not treat hot flashes of menopause and may cause hot flashes to occur. Also, raloxifene does not stimulate the breast or uterus as estrogen does.

Does raloxifene (Evista) cause weight gain? In a study of postmenopausal women taking raloxifene (Evista) for the prevention of osteoporosis, 9% of women experienced weight gain.

How long should you take raloxifene for gyno?

For men with idiopathic gynecomastia that causes discomfort and lasts more than three months, a short course (three to six months) of tamoxifen or raloxifene may be recommended.

The significant 25% reduction in global index (150 fewer events per 10,000 women taking raloxifene for an average of 3.4 years) is compatible with a favorable risk-benefit safety profile when raloxifene is used for osteoporosis treatment in postmenopausal women.

Evista is a pill taken once per day, with or without food. Most doctors recommend taking Evista at the same time each day. In research studying Evista to reduce breast cancer risk, women took the medicine for five years.

Evista may infrequently cause stroke or serious blood clots to form in the legs, lungs, or eyes.

While available information is supportive of EVISTA use for more than three years, the optimum duration of EVISTA therapy is not known.