Can Graves disease come back after RAI treatment? (2023)

Table of Contents

Can you get Graves disease again after radioactive iodine treatment?

Abstract. The use of radioactive iodine (131I) in the treatment of Graves' disease results frequently in hypothyroidism requiring thyroid hormone supplementation. Relapse of Graves' disease months after inadequate treatment with 131I is well-recognized.

(Video) The risks of secondary cancers from radioactive iodine treatment. 162
(ThyCa: Thyroid Cancer Survivors' Association, Inc.)
Can you get Graves disease after Rai?

Commonly, people develop hypothyroidism after RAI, though the rate at which this occurs within the first year after treatment depends on the radioiodine dose. The higher the dose, the higher the likelihood of hypothyroidism. Hypothyroidism can be a long-term side effect and develop years after treatment.

(Video) The risks of radioactive iodine treatment in thyroid cancer
Can thyroid function return after radioactive iodine?

The radioiodine-induced hypothyroidism is mostly irreversible. Though, early recurrences can be due to treatment failure, inadequate radioiodine dose or rarely due to Marine-Lenhart syndrome.

(Video) Health update - graves disease 2 months post RAI
(Chaotic Mom)
Does radioactive iodine get rid of Graves disease?

Graves' disease is usually treated with antithyroid drugs, radioactive iodine therapy, or surgery.

(Video) Radioactive Iodine Treatment: What to Expect Afterward
(Dr. Westin Childs)
Can hyperthyroidism come back after radioactive iodine treatment?

Recurrence of hyperthyroidism after RAI therapy may be due to inadequate dosing or early Marine Lenhart syndrome. Herein we report a rare case of recurrent Graves' hyperthyroidism occurring after 2 years of successful radioiodine treatment.

(Video) What Can I Do After Radioactive Iodine Treatment?
(Docs Adrian & Giulia - ThyroidBoss)
What causes Graves disease to come back?

Emotional or physical stress. Stressful life events or illness may act as a trigger for the onset of Graves' disease among people who have genes that increase their risk. Pregnancy. Pregnancy or recent childbirth may increase the risk of the disorder, particularly among women who have genes that increase their risk.

(Video) Is Long-term Antithyroid Use the Best Treatment for Graves Disease?
Can Graves disease go into remission twice?

It is thought unlikely that patients with recurrent Graves' hyperthyroidism would go into remission after a second course of ATD, and guidelines therefore recommend definitive treatment by RAI or Tx in case of recurrences.

(Video) Side Effects of Radioactive Iodine | UCLA Endocrine Center
(UCLA Health)
What happens after Rai for Graves?

Some people may have a feeling of tightness or swelling in their neck for a few days after treatment. This is more common if you still had a large part of your thyroid gland when you have radioactive iodine treatment. Some people also feel flushed.

How long does RAI treatment last?

Most radiation from the RAI is gone in about one week. Ask your doctor about ways to protect your salivary glands, which also absorb the RAI. Ways include sucking on sugar-free lemon candy or eating certain foods. Your doctor will have instructions on what to do, and when to do it.

(Video) Going Radioactive on Graves’
(Lee Health)
What are the long-term side effects of radioactive iodine for Graves?

Reported long-term side effects were benign thyroid nodules, multinodular benign goiter, hyperparathyroidism, and papillary thyroid carcinoma. These side effects affecting thyroid tissue were only reported in cases in which the RAI treatment aim was euthyroidism.

(Video) Radioactive Iodine Treatment (RAI 131) and Isolation
(Aubrey Lauren)

How many times can you have radioactive iodine treatment?

You may only need to have this treatment once. But it can be repeated every 3 months if needed, until there is no sign of any thyroid cancer on your scans.

(Video) Foods to AVOID If You Have Graves' Disease (These Foods Can HARM Your Thyroid)
(Dr. Westin Childs)
What is the success rate of radioactive iodine treatment?

Conclusion: Radioactive iodine treatment is an effective modality for definitive treatment of hyperthyroidism with long-term cure approaching 80%.

Can Graves disease come back after RAI treatment? (2023)
What is the safest treatment for Graves disease?

These prescription medications include propylthiouracil and methimazole (Tapazole). Because the risk of liver disease is more common with propylthiouracil, methimazole is considered the first choice when doctors prescribe medication.

Do you still have Graves disease if your thyroid is removed?

Despite this, there have been cases of Graves' disease after total thyroidectomy. Rates of recurrence are variable from 0% to 33%. Graves' disease after total thyroidectomy (removal of all visible thyroid tissue in the neck) can recur in the thyroid bed if tissue is missed during surgery or in ectopic thyroid tissue.

Why does radioactive iodine worsen Graves?

An association between radioactive iodine (RAI) therapy for GD and the development or worsening of Graves' orbitopathy (GO) is widely quoted. RAI-associated leakage of thyroid antigen(s) leads to an increased production of TSH-R antibodies that may initiate the eye injury.

Does Graves disease come back?

Even if the disease goes into remission after anti-thyroid treatment, it can come back. Follow-up appointments to check thyroid activity usually are scheduled once every six months for the first two years after the disease goes into remission.

How long does radioactive iodine last?

How long does radioiodine stay in your body? The radioiodine from your treatment will remain in your body temporarily. Most of the radioiodine not collected by your residual thyroid tissue will be eliminated during the first two days after your treatment.

How long do you take radioactive iodine for hyperthyroidism?

For most people, one dose of radioactive iodine treatment will cure hyperthyroidism. Usually, thyroid hormone levels return to normal in 8 to 12 weeks. In rare cases, the person needs a second or third dose of radioactive iodine.

Can stress bring on Graves Disease?

Thyroid conditions such as Grave's disease (hyperthyroid) and Hashimoto's thyroiditis (hypothyroid) are worsened by chronic stress so learning ways to lessen stress is your key to better health.

What autoimmune disease causes Graves disease?

Graves disease is an autoimmune disorder that involves overactivity of the thyroid (hyperthyroidism). Hallmarks of the condition are bulging eyes (exophthalmos), heat intolerance, increased energy, difficulty sleeping, diarrhea and anxiety.

What are the long term effects of Graves disease?

Graves' disease is rarely life-threatening. However, without treatment, it can lead to heart problems and weak and brittle bones. Graves' disease is known as an autoimmune disorder. That's because with the disease, your immune system attacks your thyroid — a small, butterfly-shaped gland at the base of your neck.

How often does Graves disease relapse?

Graves' disease (GD) is the most common cause of hyperthyroidism, affecting approximately 0.5% of men and 3% of women. In Europe, the first choice treatment is most often the administration of antithyroid drugs (1, 2). However, approximately half of patients relapse within two years of drug withdrawal.

Can you have Graves disease more than once?

Unfortunately, this only occurs in ~25% of patients, so Graves' disease often recurs after stopping the ATD. Frequently, patients will then elect a more permanent option such as thyroid surgery or RAI.

Do Graves disease antibodies go away?

Occasionally, the thyroid stimulating antibodies do go away in patients treated with antithyroid drugs, resulting in remission of the Graves' disease and allowing for discontinuation of the medications. However, the thyroid stimulating antibodies may return causing the Graves disease to relapse.

Can Rai cause other cancers?

Taking a closer look at the solid cancer risks, the researchers found that treatment with RAI (versus no treatment with RAI) was associated with increased risk of salivary gland cancer (by 200%), uterine cancer (by 55%), lung cancer (by 42%), and female breast cancer (by 18%).

Which of the following is the most common complication of radioiodine treatment of Graves disease?

The most common adverse reaction to medical therapy was a rash in 8 patients, followed by neutropaenia (neutrophils < 1.0 × 109/L) in 6 patients. LFT derangement was reported in 3 patients taking PTU and 1 patient taking carbimazole.

What not to do after radioactive iodine treatment?

First two days:
  1. Do not share cups, glasses, plates or eating utensils. Wash items promptly after using. ...
  2. Do not share towels or washcloths.
  3. Flush the toilet twice and rinse the sink and tub after use.
  4. Wash your towels, bed linens, underwear, and any clothing stained with urine or sweat.

What happens to the thyroid gland after Rai?

Radioactive iodine is taken up by the thyroid, and destroys the cells in the thyroid gland. This has the effect of reducing the amount of thyroxine made by the thyroid gland and may also reduce the size of the gland.

Is radioactive iodine worth it?

No. It's only used for patients with certain types of differentiated thyroid carcinomas — specifically, papillary and follicular thyroid cancer. But not even all differentiated carcinomas have the ability to take up iodine. Undifferentiated or medullary thyroid carcinomas will not benefit from iodine therapy.

What is the most common complications of radioiodine therapy?

Risks and side effects
  • Neck tenderness and swelling.
  • Nausea and vomiting.
  • Swelling and tenderness of the salivary glands.
  • Dry mouth.
  • Taste changes.
Mar 14, 2019

Does radioactive iodine completely destroy the thyroid?

The nuclear medicine team may do scans during your treatment to check where the iodine has been absorbed. The radiation will kill the thyroid gland and, if the treatment is for thyroid cancer, any thyroid cancer cells that might have traveled and settled in other organs.

Can you have radioactive iodine twice?

You may only need to have this treatment once. But it can be repeated every 3 months if needed, until there is no sign of any thyroid cancer on your scans.

Can my Graves disease come back?

The average remission rate after a course of ATD is about 50% [21]. Most recurrences occur within 4 years after discontinuation of ATD [3]. Although prognosis is excellent after 4 years without relapse [30], late recurrences do occur and only one in three patients experiences permanent remission [21].

Does radioactive iodine cause Graves disease?

For some patients who are treated with radioactive iodine to reduce the size of a goitre, there is also a small risk that they may develop Graves' disease. There is no risk that patients treated with radioactive iodine for an overactive or enlarged thyroid will lose their hair as a result of the treatment.

What are the long term side effects of radioactive iodine for Graves?

Reported long-term side effects were benign thyroid nodules, multinodular benign goiter, hyperparathyroidism, and papillary thyroid carcinoma. These side effects affecting thyroid tissue were only reported in cases in which the RAI treatment aim was euthyroidism.

How long does radioactive iodine work in the body?

How Long Does the Radioiodine Stay in the Body? The radioiodine from your treatment will remain in your body only temporarily. Most of the radioiodine not collected by your thyroid gland will be eliminated during the first two days after your treatment.

How long are you radioactive after radioactive iodine?

Small amounts of radiation from your body may trigger radiation monitors at airports, border crossings, government buildings, hospitals, and waste disposal sites for up to 3 months after treatment. Ask your doctor for advice if you will be in these areas.

You might also like
Popular posts
Latest Posts
Article information

Author: Edwin Metz

Last Updated: 06/02/2023

Views: 5668

Rating: 4.8 / 5 (58 voted)

Reviews: 81% of readers found this page helpful

Author information

Name: Edwin Metz

Birthday: 1997-04-16

Address: 51593 Leanne Light, Kuphalmouth, DE 50012-5183

Phone: +639107620957

Job: Corporate Banking Technician

Hobby: Reading, scrapbook, role-playing games, Fishing, Fishing, Scuba diving, Beekeeping

Introduction: My name is Edwin Metz, I am a fair, energetic, helpful, brave, outstanding, nice, helpful person who loves writing and wants to share my knowledge and understanding with you.